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Assessment of Risk Factors for Developmental Defects of the Enamel in Preterm

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¹Ú»ó¿¬ ( Park Shang-Yon ) - 
ÀÌÁ¦È£ ( Lee Jae-Ho ) - 
ÃÖÇüÁØ ( Choi Hyung-Jun ) - 
°­Á¤¹Î ( Kang Chung-Min ) - 

Abstract

º» ¿¬±¸´Â Á¶»ê¾Æ À¯Ä¡ÀÇ ¹ßÀ°¼º ¹ý¶ûÁú °áÇÔÀ» Á¤·®È­ÇÏ´Â Æò°¡ ±âÁØÀ» Á¦½ÃÇÏ°í, Á¶»ê¾ÆÀÇ ÀçűⰣ, Ãâ»ý ½Ã üÁß, ´Ù¾çÇÑ ÇÕº´Áõ ¹× Ä¡·á À̷¿¡ µû¸¥ ¹ßÀ°¼º ¹ý¶ûÁú °áÇÔÀǽɰ¢µµ¸¦ Á¶»çÇÏ°íÀÚ ÇÏ¿´´Ù. Á¶»ê¾ÆÀÇ ½Å»ý¾ÆÁýÁßÄ¡·á½Ç ÀÔ¿ø ¹× Åð¿ø ±â·ÏÀ» ÈÄÇâÀûÀ¸·Î Æò°¡ÇÏ¿© Ãâ»ý Á¤º¸, ÇÕº´Áõ Áø´Ü ¿©ºÎ, ºñ°æ±¸ ¿µ¾ç ¹× ±â°ü³» »ð°ü ±â°£À» Á¶»çÇÏ¿´´Ù.
±âÁ¸ÀÇ ¹ßÀ°¼º ¹ý¶ûÁú °áÇÔ Æò°¡ÁöÇ¥¸¦ ¼öÁ¤ÇÏ¿© Preterm Developmental Defects of Enamel (PDDE) index¸¦ °í¾ÈÇÏ¿´À¸¸ç, Æò°¡ÀÚ´Â ±âÁØ¿¡ ¸ÂÃß¾î Á¶»ê¾Æ À¯Ä¡ÀÇ ¹ßÀ°¼º¹ý¶ûÁú °áÇÔÀ» ¹ý¶ûÁú Àú±¤È­¿Í ÀúÇü¼ºÀ¸·Î ±¸ºÐÇÏ¿© Á¡¼öÈ­ÇÏ¿´´Ù. ÀçűⰣ 28ÁÖ ¹Ì¸¸, Ãâ»ê ½Ã üÁß 1000 g ¹Ì¸¸ÀÎ ±ºÀÇ PDDE score´Â À¯ÀÇÇÏ°Ô Áõ°¡ÇÏ¿´´Ù. ±â°üÁöÆóÀÌÇü¼ºÁõ, ±¸·çº´, ³ú½Ç³»ÃâÇ÷, ±«»ç¼º ´ëÀå¿° Áø´Ü ÀÌ·ÂÀÌ ÀÖ´Â ±º, ±â°ü³» »ð°ü Àϼö°¡ 50ÀÏ ÀÌ»óÀαº, ºñ°æ±¸¿µ¾ç Àϼö°¡ 20ÀÏ ÀÌ»óÀÎ ±º ¿ª½Ã PDDE score¸¦ À¯ÀÇÇÏ°Ô Áõ°¡½ÃÄÑ ¹ßÀ°¼º ¹ý¶ûÁú °áÇÔÀÇ À§ÇèÀÎÀÚÀÓÀ» È®ÀÎÇÏ¿´´Ù. º» ¿¬±¸´Â Á¶»ê¾Æ ¹ßÀ°¼º ¹ý¶ûÁú °áÇÔ À§ÇèÀÎÀÚ¸¦ÆľÇÇÏ¿© Á¶»ê¾ÆÀÇ ±¸°­ »óŸ¦ ¿¹ÃøÇÏ°í ¼³¸íÇϱâ À§ÇÑ ±âÃÊ Á¤º¸¸¦ Á¦°øÇÒ ¼ö ÀÖÀ» °ÍÀÌ´Ù.

This study aimed to determine the criteria for quantifying developmental defects of enamel in primary teeth in premature babies and to investigate the severity of developmental defects according to the gestational age, birth weight, systemic complications, and treatments received after preterm birth. Birth information, a history of complications, the duration of parenteral nutrition, and endotracheal intubation were investigated by retrospectively reviewing the admission and discharge records of premature babies in the neonatal intensive care unit. The Preterm Developmental Defects of Enamel (PDDE) index was designed by modifying the existing developmental defects of enamel index. Based on PDDE index, the evaluator scored developmental defects of enamel by classifying them as enamel hypomineralization and hypoplasia. The PDDE scores in the extremely preterm and extremely low birth weight groups were significantly higher than those in other groups. Furthermore, PDDE scores of premature babies with bronchopulmonary dysplasia, rickets, intraventricular hemorrhage, or necrotizing colitis were significantly higher than those in the control group. In addition, more than 50 days of endotracheal intubation and more than 20 days of parenteral nutrition were associated with significantly higher PDDE scores than those in the control group and were risk factors for developmental defects of enamel. This study provides basic information for identifying risk factors for developmental defects of enamel in premature babies.

Å°¿öµå

Preterm; Developmental defects of enamel; Gestational age; Birth weight

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